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Philadelphia chromosome

The Philadelphia chromosome is the result of a translocation between chromosomes 9 and 22 leading to the generation of aMarketing Research and Data Analysis chimeric tyrosine kinase gene, BCR-ABL. This chromosomal abnormality is associated with which of the following disorders?

(A) burkitt lymphoma

(B) chronic myeloid leukemia

(C) fanconi anemia

(D) Li-Fraumeni syndrome (LFS)

(E) von Hippel-Lindau syndrome (VHL)

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